Immune Regulation

The Immune Regulation theme provides new insight into mechanisms that control immune system development and function.

Meet our research leads

Professor Graham Anderson

Professor of Experimental Immunology

Professor Alex Richter

Professor and Honorary Consultant in Clinical Immunology

About our research

Knowledge is gained through spatial, temporal and single cell analysis of immune cells using in vivo models, which is then used to design new approaches for the prevention and treatment of human diseases.

Aims of our research

  • Define key genes, proteins and cells in the innate and adaptive immune systems that control differentiation, homeostasis and regulation of the immune response
  • Understand immunity to pathogens and how this can be used to improve vaccination strategies
  • Define the pathogenesis of immunological diseases ranging from autoimmunity to transplant rejection and how to manipulate the immune system through immunotherapy

Our staff

Meet our team of experts

Professor Adam Cunningham

Professor of Functional Immunity

Research interest: How immune responses develop to vaccines and infection and how they impact on host immune homeostasis.

Professor Kai-Michael Toellner

Honorary Professor of Adaptive Immunology

Research interest: How lymphocytes differentiate in response to pathogens or vaccines.

Professor David Withers

Honorary Professor of Immune Regulation

Research interest: Understanding how memory CD4 T-cell responses are generated and maintained.

Dr Jorge Caamaňo

Reader in Cellular Immunology

Research interest: Secondary and tertiary lymphoid tissue development and function during immune responses and inflammation.

Dr Nick Jones

Senior Lecturer

Research interest: Transplant immunology, regulatory T-cells, memory T-cells, invariant NKT cells, rejection, tolerance. 

Dr William Jenkinson

Senior Lecturer

Research interest: Investigation of mechanisms controlling T-cell development and central tolerance. 

Dr Sarah Dimeloe

Associate Professor

Research interest: Metabolism of immune cells and how this underpins their role in health and disease.

Dr Kendle Michelle Maslowski

Birmingham Fellow

Research interest: Innate immune pathways in intestinal epithelial cells and their roles in fighting infection and cancer development.

Dr David Bending

Associate Professor

Cellular and molecular mechanisms that control T-cell differentiation, function and regulation.

Dr Rebecca Drummond

Birmingham Fellow

Research interest: How organ-specific immune responses develop by studying the behaviour of tissue-resident myeloid cells. 

Professor Mark Drayson

Professor of Clinical Immunodiagnostics

Research interest: Investigation of drug redeployment strategies as a route for development of novel therapies.

Professor Sylvie Freeman

Professor of Immunohaematology

Research interest: Predicting treatment resistance in acute myeloid leukemia and myelodysplasia principally by monitoring residual disease (MRD).