Immune Regulation
The Immune Regulation theme provides new insight into mechanisms that control immune system development and function.
Meet our research leads
Professor of Experimental Immunology
Professor and Honorary Consultant in Clinical Immunology
About our research
Knowledge is gained through spatial, temporal and single cell analysis of immune cells using in vivo models, which is then used to design new approaches for the prevention and treatment of human diseases.
Aims of our research
- Define key genes, proteins and cells in the innate and adaptive immune systems that control differentiation, homeostasis and regulation of the immune response
- Understand immunity to pathogens and how this can be used to improve vaccination strategies
- Define the pathogenesis of immunological diseases ranging from autoimmunity to transplant rejection and how to manipulate the immune system through immunotherapy
Our staff
Meet our team of experts
Meet our team of experts
Professor of Functional Immunity
Research interest: How immune responses develop to vaccines and infection and how they impact on host immune homeostasis.
Professor Kai-Michael Toellner
Honorary Professor of Adaptive Immunology
Research interest: How lymphocytes differentiate in response to pathogens or vaccines.
Professor David Withers
Honorary Professor of Immune Regulation
Research interest: Understanding how memory CD4 T-cell responses are generated and maintained.
Reader in Cellular Immunology
Research interest: Secondary and tertiary lymphoid tissue development and function during immune responses and inflammation.
Senior Lecturer
Research interest: Transplant immunology, regulatory T-cells, memory T-cells, invariant NKT cells, rejection, tolerance.
Senior Lecturer
Research interest: Investigation of mechanisms controlling T-cell development and central tolerance.
Associate Professor
Research interest: Metabolism of immune cells and how this underpins their role in health and disease.
Birmingham Fellow
Research interest: Innate immune pathways in intestinal epithelial cells and their roles in fighting infection and cancer development.
Associate Professor
Cellular and molecular mechanisms that control T-cell differentiation, function and regulation.
Birmingham Fellow
Research interest: How organ-specific immune responses develop by studying the behaviour of tissue-resident myeloid cells.
Professor of Clinical Immunodiagnostics
Research interest: Investigation of drug redeployment strategies as a route for development of novel therapies.
Professor of ImmunoHaematology
Research interest: Predicting treatment resistance in acute myeloid leukemia and myelodysplasia principally by monitoring residual disease (MRD).