West Midlands to pioneer bladder cancer recurrence trials testing novel diagnostic
The test was developed in the University’s bio-incubator, the BioHub Birmingham, and the trials are the culmination of eight years of collaborative research
The test was developed in the University’s bio-incubator, the BioHub Birmingham, and the trials are the culmination of eight years of collaborative research

The at-home urine test uses highly sensitive liquid biopsy technology developed by Nonacus in conjunction with a panel of biomarkers developed by researchers from the University’s Bladder Cancer Research Centre.
Early cancer testing company, Nonacus, has announced two West Midlands-based trials to assess a new way of monitoring for recurrence of bladder cancer, using a novel test developed in collaboration with University of Birmingham researchers.
Called Galeas Bladder, the test was developed while the company incubated at the University’s bio-incubator, the BioHub Birmingham, and a previous Cancer Research UK-funded study has already shown the it can accurately and consistently detect the presence of bladder cancer from a urine sample.
The at-home urine test uses highly sensitive liquid biopsy technology developed by Nonacus in conjunction with a panel of biomarkers developed by researchers from the University’s Bladder Cancer Research Centre.
These trials are the culmination of eight years of collaborative research and development between the University of Birmingham and Nonacus, which has the potential to help the millions of patients at higher risk of bladder cancer across our country and worldwide.
Tony Hickson, Chief Business Officer at Cancer Research UK said: "As funders of much of the world-class, cutting-edge cancer research happening in the UK, we offer unique opportunities to commercial partners looking for early involvement in new discoveries. Having Nonacus on board to help transform promising findings in the lab into a new non-invasive test to diagnosis bladder cancer is a testament to how commercial collaborations have the potential to transform the lives of patients. We are looking forward to seeing the next steps as the test is developed and rolled out to the UK and beyond.”
Jeannie Rigby, CEO of Action Bladder Cancer, said " Bladder cancer can often be diagnosed late and has a high level of recurrence – which can lead to poor outcomes for patients – and bladder cancer has been neglected in terms of new research in the past. Action Bladder Cancer UK, bladder cancer patients and their families, welcome this exciting development in improving testing for bladder cancer.”
Richard Parker, Mayor of the West Midlands, commented: “Health-tech is about better care for patients, shorter waiting times and more good jobs here in the West Midlands. Through my Growth Plan we are making this one of the best places in the country to develop and roll out new treatments - from expanding our innovation clusters to supporting local medtech businesses to grow and export. The technology I’ve seen today is proof that when we back science, patients and the economy both win.”
In a region renowned for engineering, with Richard Parker as Mayor, the West Midlands is setting the pace for medical technology. Nonacus’ innovative approach to testing for bladder cancer will help save patients time and the NHS money. Life sciences is a growth sector for the West Midlands and the UK as a whole combining the power of our universities, the creativity of our businesses and the strength of our NHS.
For media information contact Ruth Ashton, University of Birmingham Enterprise, email: r.c.ashton@bham.ac.uk
About the University of Birmingham
The University of Birmingham is ranked amongst the world’s top 100 institutions, and its work brings people from across the world to Birmingham, including researchers and teachers and more than 6,500 international students from nearly 150 countries. University of Birmingham Enterprise helps researchers turn their ideas into new services, products and enterprises that meet real-world needs. We also provide incubation, and support innovators and entrepreneurs with mentoring, advice, and training, manage the University’s Academic Consultancy Service, and University of Birmingham Enterprise Operating Divisions. Follow us on LinkedIn and X.
About Nonacus
Nonacus is a leading provider of genetic testing products based in Birmingham, UK. The company works with scientists and clinicians to provide a complete workflow for primary tumour and liquid biopsy analysis with the ultimate goal of enabling enhanced care through earlier diagnosis, treatment stratification and monitoring.
Focused on delivering innovative technologies to the genomic healthcare sector through the use of cell-free circulating DNA as a non-invasive diagnostic tool and through the deployment of their advanced liquid biopsy platform, Nonacus strives to enable decentralised, cost effective and cutting-edge cancer genomics and democratise early cancer detection and monitoring globally.

Director of the Bladder Cancer Research Centre
Staff profile for Professor Rik Bryan, Director of the Bladder Cancer Research Centre and Professor in Urothelial Cancer Research, Department of Cancer and Genomic Sciences, College of Medicine and Health

Senior Research Fellow
Staff profile for Dr Douglas Ward, Senior Research Fellow, Department of Cancer and Genomic Sciences, College of Medicine and Health, University of Birmingham