Phenome Centre Birmingham

PCB TranspStudying metabolism in human health, disease and toxicology to benefit the UK and global population.


The £8M Phenome Centre Birmingham is a large metabolic phenotyping centre led by internationally-recognised metabolomics and clinical experts at the University of Birmingham, in collaboration with Birmingham Health Partners. The centre has been established as part of a UK Stratified Medicine initiative led by the Medical Research Council (MRC) to develop capacity and capability to perform large-scale metabolic phenotyping of the human population for stratified medicine. The centre will work towards improving healthy ageing and disease diagnosis and treatment to enhance patient outcome. Additionally, Phenome Centre Birmingham specialises in chemical and drug toxicology to benefit human health.

Introduction to NMR spectroscopy at Phenome Centre Birmingham

Professor Mark Viant, Executive Director of the Phenome Center Birmingham talks about the aims of the global phenome network and the state-of-the art nuclear magnetic resonance (NMR) spectroscopy instrumentation the center uses to help realise these goals.

Introduction to mass spectrometry at Phenome Centre Birmingham


Link to video on ThermoScientific website

Professor Mark Viant and Dr Rick Dunn of Phenome Centre Birmingham discuss metabolic phenotyping applied to medical research and the development of stratified medicine.

Phenome Centre Birmingham conducts metabolic phenotyping studies with the following objectives:

  • To understand molecular mechanisms associated with human ageing, disease onset and progression  
  • To identify molecular targets for nutritional, exercise or drug interventions
  • To identify metabolic biomarkers for stratification of the human population to be applied in risk stratification of developing a specific disease, in diagnosis of a disease, in defining progression or remission from a disease, and in the identification of responders and non-responders to nutritional, exercise or drug interventions

Phenome Centre Birmingham provides a collaboration project environment for performing metabolic phenotyping studies in humans and model organisms. Experts in experimental design, analytical chemistry, bioinformatics and statistics to provide all required aspects of the study from conception to biological interpretation staff the centre. 

Academic, Industry and Funding Partners:


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