TAP undertakes both methods and applied health research. We are involved in many international collaborations and lead several collaborations working to set standards for design, delivery and analysis of studies of diagnostic tests. Our main areas of research include:
- Primary studies of diagnostic test accuracy
TAP have a broad portfolio of expertise in planning, delivery and analysis of primary studies designed to assess the use of tests in healthcare.
- Systematic review of diagnostic test accuracy
Our group is also recognised for its work in the field of systematic reviews and meta-analysis of diagnostic test evaluation. We work closely with the Cochrane Screening and Diagnostic Tests Methods Group providing the editorial base for systematic reviews of diagnostic test accuracy in the Cochrane Library.
- Estimating technical properties of biomarkers
TAP has expertise in design and analysis of biological variability and interobserver variability studies. We are developing methodological guidance in this area through our work with the NIHR Birmingham Biomedical Research Centre.
- Ensuring test evaluations are fit-for-purpose
Other areas of methodological innovation include developing theory and practical applications for assessing how tests impact on decision-making and patient health.
We have experience in designing and evaluating studies of screening tests and tools. We have strong links with the Warwick Screening Group, and have collaborated on many projects.
Our group has expertise in studies using tests for the purpose of monitoring. We have investigated methodological issues for both the design and analysis of these studies.
- Prognosis and prediction rules
As well as diagnostic test evaluation, TAP works on projects developing and validating models and prediction rules. We are close collaborators with the Centre for Prognosis Research at Keele University.