These pages allow the hospital sites already participating in the OCTAVE Trial to download the latest and previous versions of most of the documentation distributed for this trial.
Please see the links below, where we provide answers to some of the frequently asked questions raised by hospital research staff. Also find details of the trial cohorts. Please note that the documents provided are password protected - contact the OCTAVE Trial Office if you do not have these details.
Trial Overview
Chief Investigator: Professor Iain McInnes
Sponsor: University of Birmingham
Funder: Medical Research Council
Disease: Rheumatic/Inflammatory conditions, cancer, chronic renal conditions, chronic liver conditions, inflammatory bowel disease, haematopoietic stem cell transplant (HSCT) and chimeric antigen receptor (CAR) T recipients.
Trial Type: Clinical Trial of an Investigational Medicinal Product (CTIMP)
Multi-centre, multi-disease, prospective observational cohort trial.
Status: Open
CPMS number: 48426
EudraCT Number: 2021-000569-33
ISRCTN: 12821688
Recruitment Start Date: 19/02/2021
Principal Investigators and their main associated site
| Main Site Name |
Principal Investigator |
| Addenbrooke’s Hospital, Cambridge |
Dr Ram Malladi |
| Glasgow Royal Infirmary, Glasgow |
Professor Stefan Siebert |
| Hammersmith Hospital, London |
Dr Michelle Willicombe & Dr David Thomas |
| John Radcliffe Hospital, Oxford |
Professor Eleanor Barnes |
| King’s College Hospital, London |
Dr Robin Sanderson |
| Queen Elizabeth Hospital, Birmingham |
Professor Daniel Rea |
| Royal Hallamshire Hospital, Sheffield |
Professor John Snowden |
| Southampton General Hospital, Southampton |
Dr Kim Orchard |
| St James’s University Hospital, Leeds |
Professor Gordon Crook |
Participant Identification Centres (PIC)
- Milton Keynes University Hospital NHS Foundation Trust
- Royal Berkshire NHS Foundation Trust