Participating sites

These pages allow the hospital sites already participating in the OCTAVE Trial to download the latest and previous versions of most of the documentation distributed for this trial.

Please see the links below, where we provide answers to some of the frequently asked questions raised by hospital research staff. Also find details of the trial cohorts. Please note that the documents provided are password protected - contact the OCTAVE Trial Office if you do not have these details.

Trial Overview

Chief Investigator:  Professor Iain McInnes
Sponsor: University of Birmingham
Funder:  Medical Research Council
Disease:  Rheumatic/Inflammatory conditions, cancer, chronic renal conditions, chronic liver conditions, inflammatory bowel disease, haematopoietic stem cell transplant (HSCT) and chimeric antigen receptor (CAR) T recipients.
Trial Type: Clinical Trial of an Investigational Medicinal Product (CTIMP)
Multi-centre, multi-disease, prospective observational cohort trial.
Status: Open
CPMS number: 48426
EudraCT Number: 2021-000569-33
ISRCTN: 12821688
Recruitment Start Date: 19/02/2021

Principal Investigators and their main associated site

 Main Site Name                                                                      Principal Investigator
Addenbrooke’s Hospital, Cambridge Dr Ram Malladi 
Glasgow Royal Infirmary, Glasgow                                       Professor Stefan Siebert
Hammersmith Hospital, London                                            Dr Michelle Willicombe & Dr David Thomas
 John Radcliffe Hospital, Oxford                                             Professor Eleanor Barnes
King’s College Hospital, London                                            Dr Robin Sanderson
Queen Elizabeth Hospital, Birmingham                                Professor Daniel Rea
Royal Hallamshire Hospital, Sheffield                                  Professor John Snowden
Southampton General Hospital, Southampton                  Dr Kim Orchard
St James’s University Hospital, Leeds                                  Professor Gordon Crook

Participant Identification Centres (PIC)

  • Milton Keynes University Hospital NHS Foundation Trust
  • Royal Berkshire NHS Foundation Trust