About

DaRe2THINK is a transformational project that will test a new way of running clinical trials at General Practices in the NHS.

The trial will use health information already collected in the NHS to reduce the time taken for research, both for patients and NHS staff. This will allow the NHS to reach new and larger groups of patients that could benefit from new treatments.

The first trial will target an important health concern, aiming to improve the health outcomes of patients with atrial fibrillation (AF), by reducing the risk of stroke, blood clots and potentially cognitive decline and vascular dementia.

DaRe2THINK is funded by the National Institute of Health Research (NIHR) Health Technology Assessment programme. The trial brings together world leading expertise from:

 

• Aston University Clinical Neurophysiology department
• Centre for Patient Reported Outcomes based at the University of Birmingham
• University of Birmingham (Institute of Cardiovascular Sciences and Institute of Applied Health Research)
• Clinical Practice Research Datalink (CPRD, part of Medicines and Healthcare products Regulatory Agency)
• Health Data Research UK
• London School of Economics and Political Science, Health Economics
• National Institute of Health Research Clinical Research Network - West Midlands 
• The Nuffield Department of Population Health at the University of Oxford London
• University Hospitals Birmingham NHS Foundation Trust
• UK Biobank