Discovery and Translational Science

Cells under a microscope

We are investigating the pathological mechanisms underpinning common illnesses throughout the body, including periodontitis, cancer, hypertension and inflammatory disease. We are pioneering the development and translation of novel compounds and drug delivery systems to enhance our treatments of disease. We are conducting world-leading research using innovative biomaterials and technology along with cell and tissue engineering to promote repair and regeneration for degenerative diseases. Our research platforms encompass the whole spectrum from discovery and translation to clinical trials while assessing best clinical practice in medicine and dentistry.

Dr Lisa HillTheme Lead
Dr Lisa Hill

Associate Professor in Ocular Disease and Drug Delivery

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Drug Discovery, Design and Repurposing

PI: Dr Hanene Ali-Boucetta Efficient intracellular delivery and targeting of small molecules and macromolecules

PI: Professor Nicholas Barnes Targeting 5-HT and P2X7 receptors to treat disease

PI: Dr Rowan Hardy Steroid metabolism and chronic inflammatory diseases

PI: Dr Richard Horniblow Novel drug delivery for treatment of intestinal disease

PI: Dr Alan Jones Design and effective delivery of bioactive small molecules. Jones Molecular Synthesis Group

PI: Dr Marie-Christine Jones New drug delivery systems and the evaluation of their behaviour in a physiological environment

PI: Dr Farhat Khanim Drug repurposing for effective treatment of blood cancers

PI: Dr Chris McConville Design, formulation and characterisation of novel dosage forms and delivery devices to improve therapeutic outcomes

PI: Dr Isolda Romero-Canelón Discovery and development of metal-based anticancer agents

PI: Dr Kimberley Roper Synthesis of novel small molecules for applications within the medical field

PI: Dr Chris Tselepis Developing novel therapies for the treatment of intestinal diseases

Transforming Patient Care

PI: Professor Julian Bion Improving the treatment and management of sepsis

PI: Professor Jamie Coleman Drug safety, adverse drug reactions and medicines optimisation

PI: Dr Anthony Cox Assessing the safe and rational use of medicines in the clinic

PI: Professor Thomas Dietrich Clinical and epidemiologic research on the causes and treatments of oral diseases

PI: Professor Kirsty Hill Dental public health and behavioural science

PI: Dr Zahraa Jalal Monitoring adherence to medicines and effective prescribing

PI: Professor John Marriott Facilitation and evaluation of drug clinical trials in paediatrics

PI: Professor Una Martin Improving the diagnosis and treatment of hypertension

PI: Dr Alexander John Morris Dental public health and epidemiology

PI: Dr Vibhu Paudyal Pharmaceutical public health, minor ailments management and self-care

PI: Dr Sarah Pontefract Patient safety, medicines optimisation and the use of electronic patient records

PI: Dr Vahid Ravaghi Exploring socioeconomic inequalities in oral health and oral health care