Discovery and Translational Science

PI: Dr Hanene Ali-Boucetta Efficient intracellular delivery and targeting of small molecules and macromolecules

PI: Professor Nicholas Barnes Targeting 5-HT and P2X7 receptors to treat disease

PI: Dr Giovanni Bottegoni Small molecule development for limited ligandability targets

PI: Dr Rowan Hardy Steroid metabolism and chronic inflammatory diseases

PI: Dr Richard Horniblow Novel drug delivery for treatment of intestinal disease

PI: Dr Alan Jones Design and effective delivery of bioactive small molecules. Jones Molecular Synthesis Group

PI: Dr Marie-Christine Jones New drug delivery systems and the evaluation of their behaviour in a physiological environment

PI: Dr Farhat Khanim Drug repurposing for effective treatment of blood cancers

PI: Dr Chris McConville Design, formulation and characterisation of novel dosage forms and delivery devices to improve therapeutic outcomes

PI: Dr Isolda Romero-Canelón Discovery and development of metal-based anticancer agents

PI: Dr Kimberley Roper Synthesis of novel small molecules for applications within the medical field

PI: Dr Chris Tselepis Developing novel therapies for the treatment of intestinal diseases

PI: Dr Geoffrey Brown Engineering the development and differentiation of haematopoietic stem cells 

PI: Dr Josette Camilleri Formulation and development of mineral trioxide aggregates for tissue restoration and repair

PI: Professor Paul Cooper Pulp biology, dental caries and mesenchymal stem cell (MSC) repair

PI: Dr Lisa Hill New regenerative therapies for glaucoma and age-related macular degeneration

PI: Professor Will Palin Photobiomodulation as a novel therapy for tissue repair and healing

PI: Dr Upen Patel Therapeutic ultrasound for the repair of the dental pulp

PI: Dr Gowsihan Poologasundarampillai Novel biomaterials for tissue engineering and regenerative medicine

PI: Dr Ben Scheven Programming mesenchymal and dental stem cells for tissue repair and regeneration

PI: Dr Richard Shelton Tissue engineering of skin, bone and oral mucosa

PI: Dr Phillip Tomson Characterisation of material directed pulp tissue repair

PI: Professor Damien Walmsley Ultrasound to improve wound healing following surgical cutting of bone and tissue

PI: Dr Keith Brain Pathophysiology of bladder overactivity

PI: Professor Iain Chapple New mechanisms and treatments for periodontitis

PI: Dr Martin Chidgey Dysfunctional cell-cell junctions in skin and cardiac disease

PI: Dr Andrew Coney Developmental hypoxia as a driver of adult cardiovascular and neuroendocrine disease

PI: Dr Alex Conner Aquaporins and GPCRs in health and disease

PI: Dr Sarah Conner Role of sperm DNA damage in male factor infertility

PI: Dr Vivek Dhir Defects in the sulphation pathway resulting in disease

PI: Dr Melissa Grant Pathobiology of oral inflammatory diseases

PI: Dr Katarzyna Gurzawska Causes and possible new treatments of bone pathology

PI: Professor Lorraine Harper Molecular pathogenesis of vasculitis

PI: Dr Josefine Hirschfeld Biological causes and treatments of periodontitis

PI: Dr Andrew P Holmes Cardiovascular and metabolic disease caused by hypoxia

PI: Professor Moritz Kebschull Pathophysiology of periodontal and peri-implant diseases

PI: Dr Sarah A Kuehne Anaerobic bacteria and their role in pathogenesis and health

PI: Professor Prem Kumar Hypoxia sensing by the peripheral chemoreceptors in health and disease

PI: Professor Gabriel Landini Oral cancer biology

PI: Professor Janice M Marshall Neural and local control of tissue blood flow in response to systemic hypoxia and exercise

PI: Professor Mike Milward Microbiology of oral inflammatory diseases

PI: Dr Clare J Ray Pathological interactions between hypoxia and hyperglycaemia in the cardiovascular system

PI: Professor Attila Sik Cellular mechanisms and the effect of altered oxygen tension on central neuronal networks and working memory

PI: Dr Robert Stephenson Morphological and functional alterations of the working myocardium associated with congenital heart disease

PI: Dr Chris Tselepis Delineating the role of iron in gastrointestinal disease

PI: Dr Sarah Waring Histomorphological identification and stratification of oral cancers

PI: Dr Malgorzata Wiench DNA methylation and chromatin organization in cancer-related gene regulation

PI: Abdullah Al Hamid Assessing pharmacovigilance and medication safety in the UK and developing countries

PI: Professor Julian Bion Improving the treatment and management of sepsis

PI: Professor Jamie Coleman Drug safety, adverse drug reactions and medicines optimisation

PI: Dr Anthony Cox Assessing the safe and rational use of medicines in the clinic

PI: Professor Thomas Dietrich Clinical and epidemiologic research on the causes and treatments of oral diseases

PI: Dr Kirsty Hill Dental public health and behavioural science

PI: Dr Zahraa Jalal Monitoring adherence to medicines and effective prescribing

PI: Professor John Marriott Facilitation and evaluation of drug clinical trials in paediatrics

PI: Professor Una Martin Improving the diagnosis and treatment of hypertension

PI: Dr Alexander John Morris Dental public health and epidemiology

PI: Dr Vibhu Paudyal Pharmaceutical public health, minor ailments management and self-care

PI: Dr Sarah Pontefract Patient safety, medicines optimisation and the use of electronic patient records

PI: Dr Vahid Ravaghi Exploring socioeconomic inequalities in oral health and oral health care

PI: Dr Steven Sadhra Occupational risk factors and workplace interventions for respiratory disorders, contact dermatitis and occupational cancer

PI: Professor John Skelton Clinical communication and language of the doctor-patient consultation