Confronting Antimicrobial Resistance (CARe)

Infections have been the major cause of mortality in human history. Only since the start of the 20th century have public health interventions, and the discovery and use of antibiotics and vaccines, drastically reduced the number of deaths due to infectious diseases in the developed world.

In low- and middle-income countries (LMICs), however, infections remain a major cause of mortality due to poor sanitation and lack of access to antibiotics and vaccines. 

Over the last decade, treatment of infections has become increasingly difficult around the world, due to the emergence of pathogens that no longer respond to existing antimicrobial therapy. As a consequence, antimicrobial resistance (AMR) is now seen as a major threat to global health.

If no action is taken, by the year 2050 AMR may claim ten million lives per year globally. Only if we act now, and consider the biological, regulatory, economic, ethical and cultural factors driving infectious diseases and AMR, can we secure a future in which infections remain preventable and treatable.

At the IGI, we are working to build global collaborations that can address the growing problem of antimicrobial resistance and support emerging research that has the potential to lead to meaningful change.

We look to inform new interventions that consider the legal, ethical and economic aspects of antimicrobials and their use.

Our team examines the evolution and transmission of antimicrobial resistance, from both a biological standpoint and through studying the historical and cultural contexts of infection and antimicrobials.

Within our research, we aim to reduce the reliance on antimicrobials and optimise their efficacy where they are used. This means developing new antimicrobials, diagnostic tools and delivery methods, while concurrently investigating the use of alternatives for use in medical and non-medical settings.

Read research by our academics

Microbiology and Infection

Focus on Birmingham expertise

Bacteria in the gut

Study discovers over 6,000 antibiotic resistance genes

The Kreft lab at Birmingham

Combining mathematical models with experiments in the laboratory

Centre for Health Law, Science and Policy

Understanding the legal and regulatory challenges

Co-Leads Professor Willem van Schaik and Professor Nicola Gale