Associate/Affiliate Principal Investigators

Institute of Metabolism and System Research Principal Investigators

Professor Leigh Breen

Professor Leigh Breen

Exercise & Health Theme Lead
Professor of Translational Muscle Physiology

Professor Leigh Breen is a leading expert in the field of skeletal muscle physiology and metabolism, with an international standing in this field of research. His research has focused on the regulatory mechanisms of human skeletal muscle remodeling, alongside translational in vitro cell approaches. By combining muscle biochemistry with stable isotope tracer techniques and comprehensive in vivo ...

Dr Justin Chu

Dr Justin Chu

Honorary Senior Lecturer

Dr Justin Chu is an Honorary Senior Clinical Lecturer in Obstetrics and Gynaecology. He completed his PhD by medical research at the Institute of Metabolism and Systems Research at the University of Birmingham and was an Academic Clinical Lecturer until his Consultancy post in 2020.

Justin is based at the Birmingham Women’s Hospital where he is the Clinical Lead of the Tommy’s ...

Professor Thomas Justin Clark

Professor Thomas Justin Clark

Consultant Gynaecologist
Honorary Professor of Gynaecology

Justin Clark was appointed as a Consultant Gynaecologist at the Birmingham Women’s and Children’s Hospital NHSFT in 2004. He was made an Honorary Professor at the University of Birmingham in 2015. Justin is dedicated to conducting relevant, high quality, patient-centred research to improve clinical outcomes.

Justin’s research team evaluates health technologies, ...

Dr Sarah J Conner

Dr Sarah J Conner

Senior Lecturer in Reproductive Biology

Sarah Conner is a Senior Lecturer in Reproductive Biology and an Honorary Research Scientist at the Birmingham Women’s Fertility Centre.

In addition to her research interests, Sarah is an enthusiastic contributor to and coordinator of Reproduction teaching across a number of undergraduate programmes in the University.

Professor Helen J. Cooper

Professor Helen J. Cooper

Professor of Mass Spectrometry
Deputy Head of School
EPSRC Established Career Fellow

Helen is Professor of Mass Spectrometry and EPSRC Established Career Fellow. Her research focuses on the development and application of advanced mass spectrometry for the analysis of biomolecules, particularly peptides and proteins. Current areas of research include liquid extraction surface analysis of biological substrates such as dried blood spots, thin tissue sections and bacterial colonies; ...

Dr Vivek Dhir

Dr Vivek Dhir

Senior Lecturer in Molecular Endocrinology
MPharm Admissions Tutor - Endocrinology, Diabetes and Metabolism

Vivek Dhir is a Senior Lecturer in Molecular Endocrinology and has published a number of high impact research papers in scientific journals as well as reviews in the fields of endocrinology, metabolism and genetics. He has received major grants from the Welcome trust and The MRC.

Vivek is keen to talk about his science and gives frequent seminars to various groups at the local, national and ...

Professor Andrew Ewer

Professor Andrew Ewer

Emeritus Professor of Neonatal Medicine

Andrew Ewer is Emeritus Professor of Neonatal Medicine based at Birmingham Women’s Hospital

Andrew has published research papers in scientific journals including Lancet, NEJM and Cochrane library, as well as reviews and an undergraduate problem-based learning book in the field of paediatrics and neonatology. He has received grants from NIHR Health Technology Assessment, NIH ...

Professor Ioannis D Gallos

Professor Ioannis D Gallos

Honorary Professor

Ioannis’ research work focusses on health issues affecting women and families living in resource-constrained settings, particularly targeting on ways to stop mothers dying from excessive bleeding during childbirth.

Every six minutes, a mother dies from losing too much blood while giving birth. The tragedy is that this is almost always preventable.

Oxytocin is the standard medicine for the ...

Professor Neil Gittoes

Professor Neil Gittoes

Consultant and Honorary Professor of Endocrinology

Professor Neil Gittoes has led the development of The Centre for Endocrinology Diabetes and Metabolism(CEDAM) through close partnership working between the University of Birmingham and a clinical services consortium across major teaching Trusts in Birmingham. Through closer integration and understanding, CEDAM has facilitated translational research in endocrinology, diabetes and metabolism and ...

Professor Janesh K. Gupta

Professor Janesh K. Gupta

Professor of Obstetrics and Gynaecology

Janesh Gupta is Professor of Obstetrics and Gynaecology working as an Honorary Consultant at Birmingham Women’s and Children’s Hospital.

Janesh has published over 175 research papers in scientific journals, book chapters, reviews and books and over 100 lectures and presentations to learned societies in the fields of fetal medicine, benign gynaecology (including abnormal uterine ...

Dr Rowan Hardy

Dr Rowan Hardy

Lecturer in Steroid Metabolism and Signalling
School of Biomedical Sciences Research Themes Lead
Verus Arthritis Career Development Fellow

I am a Versus Arthritis Fellow with extensive experience in steroid metabolism and in vivo models of chronic inflammation. Patients with chronic inflammatory diseases develop systemic complications such as muscle wasting and bone loss, which contribute to disability and reduced life expectancy. My research group is examining the roles of myeloid and mesenchymal steroid metabolism and signalling ...

Dr Shan He

Dr Shan He

Senior Lecturer of Computer Science

Dr Shan He is a Senior Lecturer in Computational Biology in the School of Computer Science, at the University of Birmingham. For more information, please see Shan's homepage.

 

Dr Tarekegn G Hiwot

Dr Tarekegn G Hiwot

Honorary Reader in Inherited Metabolic Disorders

Tarek’s research targets Alstrom Syndrome, a model of monogenic metabolic syndrome that can help us to understand severe insulin resistance and its complications.

Professor David J. Hodson

Professor David J. Hodson

Honorary Senior Research Fellow

Research in Dave’s lab uses a combination of imaging, chemical biology and genetics to understand how subtle differences in the beta cell barcode may predispose to diabetes in rodents and man.

Professor Mark David Kilby

Professor Mark David Kilby

Emeritus Professor of Fetal Medicine

Mark Kilby’s research focusses on materno-fetal health, with areas of interest including steroids and the feto-placental unit, new technologies in prenatal diagnosis, fetal in utero therapy, monochorionic twins, and maternal immunotolerance and fetal immunity.

Dr Yu-Chiang Lai

Dr Yu-Chiang Lai

Birmingham Fellow in Molecular Physiology and Biochemistry
Director of Mitochondrial Profiling Centre

Yu-Chiang is a Birmingham Fellow in the School of Sport, Exercise and Rehabilitation Sciences and affiliated in the Mitochondrial Profiling Centre (MPC), MRC-ARUK Centre for Musculoskeletal Ageing Research and the Institute of Metabolism and Systems Research (IMSR).   

Yu-Chiang’s group focuses on deciphering the signalling networks that regulate muscle metabolic functions. We ...

Dr Konstantinos Manolopoulos

Dr Konstantinos Manolopoulos

Honorary Senior Clinical Lecturer

Konstantinos is exploring the hormonal determinants of adipose tissue function in vivo, and the factors leading to adipocyte dysfunction in obesity.

Professor Claudio Mauro

Professor Claudio Mauro

Co-Lead of Research Strategy
Professor of Metabolism and Inflammation
British Heart Foundation Senior Basic Science Research Fellow

Professor Mauro trained as biochemist and cellular biologist before starting to approach immunological questions with his own group, motivated by the recent ‘renaissance’ in the interest in metabolism in widespread fields of the basic and clinical science.

The Mauro’s group investigates the interconnections between metabolic and inflammatory pathways and how systemic and local ...

Professor Krish Nirantharakumar

Professor Krish Nirantharakumar

Professor in Health Data Science and Public Health
Honorary Consultant in Public Health Medicine
Deputy Director of the Institute of Applied Health Research

Krish is a senior clinical academic with substantial experience in health informatics research.

He is the theme lead for health informatics and Professor in Health Data Science and Public Health at the Institute of Applied Health Research, with affiliation to the Institute of Metabolism and Systems Research, University of Birmingham. Krish has particular interests in developing novel ...

Dr Abd Tahrani

Dr Abd Tahrani

Honorary Professor of Medicine

Abd Tahrani is an Honorary Professor of Medicine at the University of Birmingham and an Honorary Consultant in Endocrinology, Diabetes and Weight Management at the University Hospitals of Birmingham NHS Foundation Trust. He currently has a substantive role at Novo Nordisk global obesity team. Abd has wide ranging experience in the field of obesity academically and clinically. He worked ...

Dr Jennifer Tamblyn

Dr Jennifer Tamblyn

Honorary Clinical Lecturer

Jennifer is an Honorary Clinical Lecturer at Birmingham Women’s & Children’s Hospital. Funded by a Wellbeing of Women Clinical Research Fellowship, Jennifer utilised her PhD to explore vitamin D metabolism in pregnancy, and the potential effects of vitamin D upon immune cell function within the maternal placenta at the University of Birmingham. To help answer these questions ...

Professor Peter Tino

Professor Peter Tino

Professor of Complex and Adaptive Systems

Peter Tiňo is a Professor of Complex and Adaptive Systems at the School of Computer Science at the University of Birmingham. He is the author of over 160 research articles in the areas of dynamical systems, machine learning, natural computation and fractal geometry. Peter has been awarded three outstanding Journal Paper of the Year awards and the Head of School's Excellence in Teaching Award.

Professor Mark Viant

Professor Mark Viant

Professor of Metabolomics
Director of Phenome Centre Birmingham
Past President of the International Metabolomics Society

60 second video iconProfessor Mark Viant’s expertise lies in the field of metabolomics. His research spans from method development in analytical chemistry and bioinformatics through to the application of metabolomics to environmental toxicology.

Dr Gareth Wallis

Dr Gareth Wallis

Head of Research and Knowledge Transfer
Associate Professor (Reader) in Exercise Metabolism and Nutrition

Dr Wallis is an Exercise Scientist with major interests in Nutrition and Metabolism. He studies dietary influences on exercise metabolism, with a particular focus on macronutrients and their roles in performance, training adaptation and health.

Dr Ralf Weber

Dr Ralf Weber

Director of Bioinformatics, Phenome Centre Birmingham (PCB)

Ralf Weber is the Director of Bioinformatics for the Phenome Centre Birmingham. His research team’s interests include the development and application of data processing, biostatistics and data mining tools to facilitate biochemical annotation and interpretation of clinical and toxicological metabolomics data.

Dr Martin Whitham

Dr Martin Whitham

Senior Lecturer in Exercise Metabolism

Dr Martin Whitham is an integrative physiologist primarily interested in endocrinology and tissue cross-talk in the context of exercise. Since physical activity represents a broad and effective preventative treatment for a host of non-communicable diseases, the main focus of his group’s work is to examine the role small vesicles, exosomes and proteins play in inter-tissue signalling during ...