Lower Limb Amputation Pillar In 'ROSSINI-Platform' Rossini PlatformRecruitment & Participating SitesCardiacGroinLower Limb AmputationNeurosurgeryData & PrivacyContact Us ROSSINI-Platform aims to recruit up to 26,000 patients over a period of 5 years from NHS Trusts across the UK. Interventions 1) Double skin preparation vs. single preparation 2) Continuous vs. interrupted skin closure 3) Incisional negative pressure wound therapy (iNPWT) vs. standard practice Key Inclusion Criteria Adults undergoing MLLA by a vascular surgeon. LLA Team Members Lead: David Bosanquet Co-PI: Gavin Murphy Pillar-Specific Documentation LLA Protocol to be added when approved.