Principal Investigators

Dr Akerman is interested in answering fundamental questions about gene regulation in diseased and healthy pancreatic beta cells through integrated use of molecular, genomic, computational and systems biology. Her team aims to understand how various types of noncoding DNA elements interact to establish gene expression in the pancreatic beta cell. With the support of Diabetes UK, Akerman lab has ...

John Allotey is a lecturer in epidemiology and women’s health at the WHO Collaborating Centre for Global Women's Health within the Institute of Metabolism and Systems Research. He has almost a decade of experience in academic clinical research, primarily in the field of maternal health. His research interests lie in the development, evaluation and implementation of prognostic models ...

Davide Calebiro is a Professor of Molecular Endocrinology and Wellcome Trust Senior Research Fellow at the Institute of Metabolism and Systems Research (IMSR) and Co-Director of the Centre of Membrane Proteins and Receptors (COMPARE) of the Universities of Birmingham and Nottingham

He leads a multidisciplinary research team comprising biologists, chemists, physicists, engineers and computer ...

Sarah Conner is a Senior Lecturer in Reproductive Biology and an Honorary Research Scientist at the Birmingham Women’s Fertility Centre.

In addition to her research interests, Sarah is an enthusiastic contributor to and coordinator of Reproduction teaching across a number of undergraduate programmes in the University.

Professor Coomarasamy is the Director of Tommy’s National Centre for Miscarriage Care and Research. His research interests are in fertility, early pregnancy and global women’s health.

Gaby is an Associate Professor in Cellular Metabolism and a Senior Fellow of the Higher Education Academy.  She has an interest in energy homeostasis, particularly in fuel sensing mechanisms that may play a role in diabetes and obesity.

Adam's primary research focus is clinical trials in early pregnancy care, with a particular focus on miscarriage, infertility and global women’s health. As Associate Professor of Maternal Health Clinical Trials, he collaborates with the Birmingham Clinical Trials Unit to manage a portfolio of national and international clinical trials. He is also a senior consortium member of the Tommy' ...

Dr Rima Dhillon-Smith is a clinical lecturer based at the  Birmingham Women’s and Children’s Hospital NHS Foundation Trust. She combines her academic work with clinical duties as a registrar in Obstetrics and Gynaecology.  Rima’s main research interests lie in reproductive endocrinology, subfertility, paediatric gynaecology and early pregnancy.  She is a key ...

Vivek Dhir is a Senior Lecturer in Molecular Endocrinology and has published a number of high impact research papers in scientific journals as well as reviews in the fields of endocrinology, metabolism and genetics. He has received major grants from the Welcome trust and The MRC.

Vivek is keen to talk about his science and gives frequent seminars to various groups at the local, national and ...

Sarah Dimeloe is a Birmingham Fellow working across the Institutes of Immunology and Immunotherapy (III), and Metabolism and Systems Research (IMSR).

Research in Sarah’s lab is focused on the metabolism of immune cells and how this underpins their role in health and disease.

Dr Dimeloe is a member of the 2017/18 Birmingham Fellows.

 

Dr Foster is an established research figure in the fields of endocrinology, cancer and drug discovery. With over two decades of experience in both academic and industrial environments, he has extensive research knowledge on a wide-range of areas. He is an author on over 55 scientific peer-reviewed papers, covering endocrinology, oncology, inflammation, cardiology, and drug development, and has ...

Dr Gallagher's research interests are in: image analysis of human sperm motility; Biological fluid dynamics; Asymptotic and numerical methods to investigate problems in fluid mechanics; Mathematical modelling of fluid structure interaction; Numerical modelling of stability of Non-Newtonian fluids.

Caroline Gillett is the Assistant Professor in Patient and Public Involvement and Engagement in the Institute of Metabolism and Systems Research (IMSR). She manages IMSR’s Public and Patient Engagement and Involvement Strategy, including devising and delivering activities, training and events to engage diverse communities with IMSR’s highly societally relevant research portfolio.

She ...

Professor Neil Gittoes is Consultant Endocrinologist at the Queen Elizabeth Hospital, Birmingham and Honorary Professor of Endocrinology at the University of Birmingham. He is inaugural Head of the Centre of Endocrinology, Diabetes and Metabolism (CEDAM), a partnership organisation across NHS provider organisations and the University of Birmingham aiming to optimise translational research ...

Caroline’s research is focussed on the trafficking and signalling of membrane proteins, and how their impairments contribute to endocrine and metabolic disease. She is currently establishing her research group investigating metabolic GPCRs and how they integrate hormonal signals to regulate appetite. 

As an Assistant Professor in Steroid Metabolism and Signalling I have expanded upon a successful Versus Arthritis Early Career Development fellowship to become a leader in the field of steroid metabolism and inflammation and in vivo models of chronic inflammation. My research group is examining the roles of myeloid and mesenchymal steroid metabolism and signalling in mediating inflammatory ...

Martin’s group investigates the role vitamin D  plays in human health beyond its effects on bone. They focus on vitamin D and immune function, and how this influences infectious diseases, pregnancy and autoimmune disease.

Jan is Clinical Associate Professor in Paediatric Endocrinology and Diabetes, based at the IMSR and at the Department of Endocrinology at the Birmingham Children’s Hospital. His research focuses androgen metabolism. He is interested in inborn errors of steroid metabolism, in particular conditions affecting androgen generation. He combines clinical phenotyping and genetic analysis with in ...

Dr Leandro Junges is a Research Fellow at the Centre for Systems Modelling and Quantitative Biomedicine (IMSR - UoB). He has a particular interest in the development and application of quantitative methods to help understanding biomedical systems and develop personalised predictions in healthcare, especially in the context of neuroscience.

Part of the Centre for Systems, Modelling and ...

Niki Karavitaki is Clinical Associate Professor in Endocrinology and Honorary Consultant Endocrinologist at the Queen Elizabeth Hospital Birmingham where she co-leads the Pituitary Service and Pituitary MDT.

Her research and clinical interests focus on hypothalamo-pituitary disease (particularly sellar and parasellar tumours and hypopituitarism) covering pathogenesis, management and long-term ...

Jackson’s research is about andrology and its application in the diagnosis and treatment of infertility, with direct impact on care and quality of life of the patients involved and the birth of the next generation. 

Christian’s research is focused on developing novel experimental and analytical approaches to map metabolic pathway activities without assuming a particular metabolism model.

Kendle is a Birmingham Fellow working across the Institutes of Immunology and Immunotherapy (III), and Metabolism and Systems Research (IMSR).

Research in Kendle’s lab is focussed on understanding innate immune pathways in intestinal epithelial cells and their roles in fighting infection and cancer development.

Chris McCabe is Professor of Molecular Endocrinology at the University of Birmingham. He works on mechanisms of endocrine cancers, including thyroid, breast and head and neck tumour models. Specifically, the research of the McCabe group focuses on the action of the sodium iodide symporter NIS in thyroid tumours; assessment of the role of the proto-oncogenes PTTG and PBF in thyroid, breast, and ...

Dr Mueller is interested in enzyme-catalysed reactions that modulate hormone function and act as biological switches. One of these transformations is the dynamic sulfation and de-sulfation of steroid hormones. Dr Mueller’s research group studies these sulfation pathways, using a variety of biochemical, bioanalytical and cell biological techniques.

Jon has authored more than 25 primary ...

Professor Manfred Opper is interested in the development and the theoretical analysis of methods for probabilistic inference in machine learning using techniques of statistical mechanics and statistics. In recent years he has worked especially in the area of data assimilation, where he has developed approximations for inference in stochastic differential equations, Markov jump processes and ...

Dr Alessandro Prete completed his training in Endocrinology and Diabetes in Rome, Italy. In 2016, he joined the Institute of Metabolism and Systems Research at the University of Birmingham. Since 2018, he is a Diabetes UK Sir George Alberti Research Fellow and is currently working towards a PhD. The title of his PhD thesis is "Exploring the metabolic impact of mild autonomous cortisol excess ...

Cristina Ronchi is a clinician scientist with long-standing translational expertise in endocrine tumors. Her research field mostly focuses on genetic studies and investigations of molecular markers involved in the pathogenesis of adrenal tumours in general and prognosis of adrenocortical cancer. She is particularly active in research dissemination and collaborates with several world-leading ...

Dr Atif Shahzad is a research fellow and lead for MSc Biomedical Innovation program at the Institute of Metabolism and Systems Research, University of Birmingham. He is associated with the Centre for Systems Modelling and Quantitative Biomedicineand also holds an honorary position at the National University of Ireland (NUI), Galway. Atif is interested in need-led health technology innovation ...

 

 

Vicki is interested in thyroid biology and the molecular pathogenesis of thyroid disease. Her research focuses on improving existing treatments and identifying novel therapies in thyroid cancer.

Angela is a steroid and analytical chemist who leads and manages the research work of the Steroid Metabolome Analysis Core (SMAC), under the supervision of Professor Wiebke Arlt. SMAC is a team consisting of scientists, who develop, optimise and validate mass spectrometry methods which are applied to laboratory based research, clinical research and clinical trials.

Angela’s research ...

Professor Daniel Tennant is a Professor of Biochemistry in the Institute of Metabolism and Systems Research (IMSR), situated on the second floor of the Institute of Biomedical Research. He uses stable isotope tracers to investigate changes in the use of nutrients in conditions where oxygen is limiting (hypoxia), or in the presence of genetic mutations that induce a hypoxia-like response. Dan ...

Professor John Terry is Interdisciplinary Professorial Fellow: a post he holds jointly across Mathematics, Computer Science and the Institute for Metabolism and Systems Research. John is also the recipient of a prestigious EPSRC Established Career Fellowship, as well as being an EPSRC Public Engagement Championwithin Computer Science. John’s research transcends traditional discipline ...

Professor Shakila Thangaratinam is Dame Hilda Lloyd Chair of Maternal and Perinatal Health at the University of Birmingham, and leads the Maternal and Reproductive Health Theme (Jan 2020-). She is the co-Director of WHO Collaborating Centre for Global Women’s Health and academic lead for Women’s Health in Birmingham Health Partners. As Consultant Obstetrician she ...

Patricia is an MRC Skills Development Fellow based in the Institute of Metabolism and Systems Research (IMSR). Her research uses cutting-edge experimental and computational research methods to investigate the mechanisms underpinning obesity-induced type 2 diabetes (T2D). She is particularly interested in understanding how intracellular fatty acid storage, mobilisation, and metabolism cause ...

Dr Wakerley is a leading consultant neurologist and expert in headache. He is also an Honorary Senior Clinical Lecturer within the Institute of Metabolism and Systems Research.

Part of the Centre for Systems, Modelling and Quantitative Biomedicine

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Professor Zamora has developed an academic career at the University of Madrid in the Biomathematics department as an Associate Professor of Biostatistics. He has been appointed as Non-Clinical Senior Lecturer of Perinatal statistics in BARC (Barts Research Centre for Women’s Health) in Queen Mary University of London.

Professor Zamora has an outstanding track record of delivering ...

Dr Eder Zavala is an applied mathematician jointly appointed across the School of Mathematics, Computer Science, and the College of Medical and Dental Sciences. His work focuses on interdisciplinary research spanning mathematics, computational and biomedical sciences. Eder has held an MRC Skills Development Fellowship and a EU Horizon 2020 secondment to develop quantitative methods for the ...