Dr Roland Arnold PhD
Theme Lead – Genomics & Bioinformatics
Roland Arnold is a specialist in the analysis of molecular alterations in cancer, and leads the Bioinformatics for Cancer and Disease Group in the Institute of Cancer and Genomic Sciences. He is a bioinformatician (computational biologist) by training and expert in the analysis of the ‘big data’ generated by modern high-throughput biological studies, such as cancer genome sequencing to detect mutations and other aberrations in tumour DNA, and especially events at the RNA level.
His work spans a wide range of research questions, including changes in gene splicing, novel methods to interpret gene expression patterns, and tailor-made analyses that integrate different biological data-types. Since his move from Oxford to Birmingham in 2017, he has been collaborating with the Bladder Cancer Group to understand and analyse patient-derived genomic data from the Bladder Cancer Prognosis Programme in order to identify biomarker candidates for disease detection and stratification.
He regularly supervises students at the Masters and PhD level, working on exciting genomics and bioinformatic projects. He also collaborates with different biologists and medical scientists to develop new insights into different cancer types (with a focus on urothelial/bladder and colorectal cancers), and to understand the basic biology of gene splicing.